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Alternative Medicine

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Clofibrate

 Herbs
 Interactions with Supplements
 Interactions with Herbs
 References


Alternative Medicine
The following information is specific for alternative and complementary medicine. For additional evidence-based information on diseases, conditions, symptoms, diagnosis, treatment and wellness issues, continue searching the Healthwise Knowledgebase.


Also indexed as:

Atromid-S



Clofibrate is a drug used to lower cholesterol in people with high blood cholesterol. It is rarely used, due to the possibility of liver damage and the availability of safer, more effective drugs.

Herbs

Summary of Interactions for Clofibrate

Depletion or interference Vitamin B12*
Adverse interactionNone known
Side effect reduction/prevention Milk thistle*
Supportive interactionNone known
Reduced drug absorption/bioavailabilityNone known


An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Supplements

Vitamin B12

Clofibrate has been reported to reduce absorption of vitamin B12.1

Interactions with Herbs

Milk thistle (Silibum marianum)

Although there have been no clinical studies, use of milk thistle with clofibrate may theoretically lower the risk of liver side effects associated with the drug. People may take a standardized milk thistle extract supplying 70-80% silymarin at an amount of 200 mg three times per day.

References

  1. Robinson C, Weigly E. Basic Nutrition and Diet Therapy. New York: Macmillan, 1984, 46-54.

Last Review: 09-07-2006

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.



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