Alternative Medicine
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Losartan is used alone or in combination with hydrochlorothiazide (Hyzaar®) in the treatment of high blood pressure. It is a type of drug called an angiotensin II receptor antagonist.
An asterisk (*) next to an item in the summary
indicates that the interaction is supported only by weak, fragmentary,
and/or contradictory scientific evidence.
Losartan has caused significant increases in blood potassium levels.1 Potassium supplements, potassium-containing salt substitutes (No Salt®, Morton Salt Substitute®, and others), and even high-potassium foods (primarily fruit) should be avoided by those taking losartan, unless directed otherwise by their doctor.
The intestinal absorption of losartan may be reduced up to 10% if taken with food.2 Although this is a minor reduction, losartan should be taken an hour before or two hours after food for maximum effectiveness.
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