Examples
|
| Cotazym, Creon, Pancrease, Pancrease MT, Ultrase | pancrelipase | |
How It Works
Enzymes help a person who has
cystic fibrosis digest food by replacing digestive
enzymes that are normally released by the
pancreas. Pancrelipase is available in tablet, powder,
or capsule form and is usually taken before eating. Capsules can be swallowed
whole or be opened and sprinkled on food.
Why It Is Used
These enzymes are used by people who have cystic fibrosis whose
pancreatic ducts are blocked. The blockage prevents digestive enzymes that are
made by the pancreas from reaching the intestines, where they are needed for
digestion.
How Well It Works
Enzyme supplements can replace natural enzymes so that fat and
proteins can be absorbed properly, which improves nutrition and reduces fatty
stools.
People with cystic fibrosis who receive enzyme replacement therapy
can eat the same foods as anyone else.
Side Effects
- Taking too little medicine can cause nausea,
stomach cramps, or diarrhea.
- Very strong enzymes or taking too many
enzymes can lead to stomach irritation, constipation, intestinal scarring, or
blockage of the intestines.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
- Most people who have cystic fibrosis need to
take digestive enzymes with meals and snacks.
- Some products work
better than others. Generic substitutes may not work as well as brand names. Be
sure to talk to your doctor about which enzymes work best or before you switch
products.
- Different people need different amounts of enzymes. Some
people may have to take several enzymes with each meal, while others may need
to take only a few.
- Enzymes may not work as well if you have too
much acid in your stomach. Some people need to take another medicine to stop
the stomach from making too much acid.
- Coated enzymes will not be destroyed by stomach acid before they
reach the intestines.
Complete the new medication information form (PDF) 
(What is a PDF document?)
to help you understand this medication.
Credits
| Author | Debby Golonka, MPH |
| Editor | Susan Van Houten, RN, BSN, MBA |
| Associate Editor | Pat Truman, MATC |
| Primary Medical Reviewer | Michael J. Sexton, MD - Pediatrics |
| Specialist Medical Reviewer | Susanna McColley, MD - Pediatric Pulmonology |
| Last Updated | June 26, 2007 |
