Restless legs syndrome is a condition caused by uncomfortable
sensations in the legs that produce an intense, often irresistible urge to move
the legs. This can lead to sleep disturbance and severe fatigue that interferes
with daily activities.
These sensations are described as "pins and needles," prickling,
creeping, crawling, tingling, and sometimes painful. They most often occur in
the evening when the person is attempting to relax or sleep. Moving the legs
can temporarily relieve these sensations.
The cause of this syndrome is often not known. Certain drugs (such
as antidepressants), pregnancy, or iron deficiency or related anemia can
trigger it.
Restless legs syndrome can be treated with drugs such as those that
increase the brain chemical dopamine (levodopa or dopamine agonists), pain
medications (opioids), or anticonvulsants (gabapentin) to control leg movements
and assist with sleep.
