Topic Overview
What is group B streptococcal infection?
Group B
streptococcal (group B strep) infection is a serious bacterial infection that
is a leading cause of death and disability in newborns.
In the
1970s, about half of newborns with group B strep infection died. Today, due to
early recognition and aggressive treatment of the infection, far fewer cases
end in death.
What causes group B streptococcal infection?
Group
B strep bacteria normally exist in the intestine, vagina, or rectum. A pregnant
woman can transmit the bacteria to her fetus during delivery. Between 15% and
30% of mothers are carriers of group B streptococcal bacteria, which means that
they carry the bacteria but have no illness from it. It is unclear why some
babies get group B strep infection and others do not.
Newborns may
develop the infection hours after birth or during the first week of life, or it
may happen several months later. Newborns who develop group B strep within the
first week are most always infected by their mothers. It's not clear how babies
who develop the infection later are exposed to the bacteria.
What are the symptoms?
Newborns infected with
group B strep within the first 6 days of life may get a blood infection (sepsis) or lung infection (pneumonia). Symptoms of late-stage group B strep (7
days to 3 months of age) may include high or low body temperature,
irritability, low energy, raised respiratory rate, and trouble feeding. An
infection of the fluid or tissues that surround the brain and spinal cord
(meningitis) could occur in the early or late stage.
Newborns thought to be infected with group B strep need medical care right
away, as the infection can be deadly.
How is group B streptococcal infection diagnosed?
Guidelines suggest that all pregnant women have prenatal testing (rectal
and vaginal cultures) for group B strep between 35 to 37 weeks of
pregnancy.1 Babies suspected of being infected are
diagnosed at birth by testing their blood or spinal fluid or both for group B
strep bacteria.
How is it treated?
Pregnant women with group B
strep infection or who are carriers of
group B strep will be given antibiotics prior to
delivery to prevent transmission of the bacteria to the newborn during
delivery. Women who are pregnant and who have previously given birth to a child
with group B strep infection, or who have had tests that show they carry the
bacteria, should be treated with antibiotics.
Newborns with the
infection will also be given antibiotics. In addition to antibiotics,
supportive care including fluids and ventilation will be given if needed. In
some cases, a health professional will treat a newborn that is suspected of
having group B strep infection before test results have shown infection. This
is because not treating strep B infection in newborns can result in illness or
death.
Having a baby by
cesarean section does not prevent the transmission of
group B strep bacteria.
