Featured Physicians Featured Physicians
In the News In the News
Hospitals, Facilities and Services Hospitals, Facilities and Services
US Family Health Plan US Family Health Plan
Outpatient Services Outpatient Services
Health Information Health Information
Health and Fitness Tools Health and Fitness Tools
Calendar of Events Calendar of Events
Medical Education Medical Education
Research & Clinical Trials Research & Clinical Trials




       



Health Information

Health Information

Back to Health Library   Print This Page Print    Email to a Friend Email
Quinine sulfate for malaria

Quinine sulfate for malaria

Examples

Generic NameChemical Name
quinine sulfate plus an antibiotic such as doxycycline or tetracycline
quinine sulfate plus clindamycin
quinine sulfate plus pyrimethamine-sulfadoxine
quinine sulfate (rarely used alone)

How It Works

Quinine sulfate prevents the development of malaria parasites in the blood.

To treat malaria, you can take quinine sulfate alone for 3 to 7 days, but it is more commonly used in one of three different combinations:

  • Quinine sulfate plus doxycycline or tetracycline is taken for 7 days.
  • Quinine sulfate plus pyrimethamine-sulfadoxine is taken as a single dose of three tablets.
  • Quinine sulfate plus clindamycin is taken for 7 days.

You usually take quinine sulfate as a tablet (orally).

Why It Is Used

Quinine sulfate plus another medication is the medication of choice for chloroquine-resistant malaria (where chloroquine is no longer effective against the malaria parasite).

How Well It Works

Quinine sulfate is effective against all species of Plasmodium.

Side Effects

Side effects of quinine sulfate include:

  • Nausea.
  • Blurred vision.
  • Headache.
  • Ringing in the ears.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Quinine sulfate given through a needle directly into a vein (intravenously, or IV) is not available in the United States, but intravenous quinidine gluconate, as a substitute, works just as well.

Complete the new medication information form (PDF) Click here to view a form. (What is a PDF document?) to help you understand this medication.

Credits

AuthorMaria G. Essig, MS, ELS
EditorSusan Van Houten, RN, BSN, MBA
Associate EditorDenele Ivins
Associate EditorPat Truman, MATC
Primary Medical ReviewerMartin Gabica, MD - Family Medicine
Specialist Medical ReviewerW. David Colby IV, MSc, MD, FRCPC - Infectious Disease
Last UpdatedMay 16, 2007