Total lymphoid irradiation uses radiation to limit the production of
white blood cells (lymphocytes). These cells help the
body's immune system destroy foreign cells and fight infection. The treatment
was first developed to treat
Hodgkin's lymphoma, a form of cancer, and has been
used successfully to treat people with
rheumatoid arthritis, which, like
multiple sclerosis (MS), is an
autoimmune disease.
In theory, total lymphoid irradiation may help prevent progression of
MS by limiting the production of lymphocytes and thus limiting the activity of
the immune system. The results of studies done so far have failed to show any
benefit.
Total lymphoid irradiation remains an experimental treatment for MS.
The treatment may be toxic and potentially dangerous and, in general, is not
recommended.
Side effects of this treatment may include:
