Search Health Information
Heart Attack and Unstable Angina
Overview
What is a heart attack?
A heart attack occurs
when blood flow to the heart is blocked. Without blood and the oxygen it
carries, part of the heart starts to die. A heart attack doesn't have to be
deadly. Quick treatment can restore blood flow to the heart and save your
life.
Your doctor might call a heart attack a myocardial
infarction, or MI. Your doctor might also use the term
acute coronary syndrome
for your heart attack or
unstable angina.
What is angina, and why is unstable angina a concern?
Angina (say "ANN-juh-nuh" or "ann-JY-nuh") is a type of chest pain or
discomfort that occurs when there is not enough blood flow to the heart. Angina
can be dangerous. So it is important to pay attention to chest pain, know what
is typical for you, learn how to control it, and understand when you need to
get treatment.
There are two types of angina:
-
Stable angina
is chest pain that has a typical
pattern. It happens when your heart is working harder and needs more oxygen,
such as during exercise. The pain goes away when you rest.
-
Unstable angina
is chest pain that is unexpected, and
resting or taking nitroglycerin may not help. Your doctor will probably
diagnose unstable angina if you are having chest pain for the first time or if
your pain is getting worse, lasting longer, happening more often, or happening
at rest.
Unstable angina is a warning sign that a heart attack may
happen soon, so it requires treatment right away. But if you have any type of
chest pain, see your doctor.
What causes a heart attack?
Heart attacks happen
when blood flow to the heart is blocked. This usually occurs because fatty
deposits called
plaque
have built up inside the
coronary arteries
, which supply blood to the heart. If a plaque breaks open, the
body tries to fix it by forming a clot around it. The clot can block the
artery, preventing the flow of blood and oxygen to the heart. See a picture of
how plaque causes a heart attack
.
This process of plaque buildup in
the coronary arteries is called coronary artery disease, or CAD. In many
people, plaque begins to form in childhood and gradually builds up over a
lifetime. Plaque deposits may limit blood flow to the heart and cause angina.
But too often, a heart attack is the first sign of CAD.
Things
like intense exercise, sudden strong emotion, or illegal drug use (such as a
stimulant, like cocaine) can trigger a heart attack. But in many cases, there
is no clear reason why heart attacks occur when they do.
What are the symptoms?
The most common symptom of
a heart attack is chest pain.
- Many people describe the pain as discomfort, pressure,
squeezing, or heaviness in the chest.
- People often put their fist to their chest when they describe
the pain.
- The pain may spread down the left shoulder and arm and to
other areas
, such as the back, jaw, neck, or right arm.
Many people also have at least one other symptom, such
as:
- Pain in the upper belly, often mistaken for heartburn.
- Sweating.
- Nausea and vomiting.
- Trouble breathing.
- A feeling that their heart is racing or pounding (
palpitations
).
- Feeling weak or very tired.
- Feeling dizzy or fainting.
Not everyone has the classic symptom of chest pain during
a heart attack. Women, older adults, and people with diabetes are slightly more
likely to have other symptoms such as shortness of breath, nausea, back pain,
or jaw pain.
What should you do if you think you are having a heart attack?
If you have symptoms of a heart attack, act fast. Quick
treatment could save your life.
If you are having chest pain and
your doctor has prescribed nitroglycerin for angina:
- Take 1 dose of nitroglycerin and wait 5 minutes.
- If the chest pain doesn't improve or it gets worse,
call 911
or other emergency services. Describe your symptoms, and say that you
could be having a heart attack.
- Stay on the phone. The emergency operator will tell you what
to do.
- After you call for help, chew 1 adult-strength aspirin or 2 to
4 low-dose aspirin unless you cannot take aspirin because of allergy or some
other reason. Aspirin helps keep blood from clotting, so it may help you
survive a heart attack.
If you are having chest pain and you do not have nitroglycerin:
-
Call
911
or other emergency services now. Describe your symptoms, and say that you could
be having a heart attack.
- Stay on the phone. The emergency operator will tell you what
to do.
- After you call for help, chew 1 adult-strength aspirin or 2 to
4 low-dose aspirin unless you cannot take aspirin because of allergy or some
other reason. Aspirin helps keep blood from clotting, so it may help you
survive a heart attack.
The best choice is to go to the hospital in an ambulance.
The paramedics can begin lifesaving treatments even before you arrive at the
hospital. If you cannot reach emergency services, have someone drive you to the
hospital right away. Do not drive yourself unless you have absolutely no other
choice.
If you think you are having unstable angina but you are
not sure, follow the steps listed above. Unstable angina can lead to a heart
attack or death, so you need to have it checked right away.
How is a heart attack treated?
If you go to the
hospital in an ambulance, treatment will be started right away to restore blood
flow and limit damage to the heart. You may be given medicines, including:
- Aspirin (if you have not already taken some) and other
medicines to prevent blood clots.
- Medicines that break up blood clots (thrombolytics). To work,
these must be given within a few hours of the start of the heart attack.
- Medicines to decrease the heart's workload, ease pain, and
treat abnormal heart rhythms, which can be life-threatening.
At the hospital, you will have tests, such as:
-
Electrocardiogram (EKG or ECG)
. An EKG can detect
signs of poor blood flow, heart muscle damage, abnormal heartbeats, and other
heart problems.
- Blood tests, including tests to see whether cardiac
enzymes
are high. Having these enzymes in the blood is
usually a sign that the heart has been damaged.
If these tests show that you may be having a heart
attack, you may have a
cardiac catheterization
. For this test, the doctor
puts a thin, flexible tube (called a catheter) through an artery in the groin
or arm and carefully guides it into the heart. (See a picture of
catheter placement
.) A dye is injected that makes the coronary arteries show up
on a computer screen. The doctor then can see if the coronary arteries are
blocked and how your heart is working.
If cardiac catheterization
shows that an artery is blocked, the doctor may do
angioplasty
right away. The doctor guides the catheter
into the narrowed artery, and a small balloon at the end of it is inflated.
This widens the artery to help restore blood flow. Often a small wire-mesh tube
called a
stent
is placed to keep the artery open. See a picture
of
angioplasty with stent placement
.
Angioplasty, with or without a stent, is the preferred treatment for a
heart attack. But if angioplasty is not available or cannot be done soon,
“clot-busting” thrombolytic medicines may be used. Or the doctor may do
emergency
bypass surgery
to redirect blood around the blocked
artery.
After these treatments, medicines
are given to prevent clots, reduce the heart’s workload, and lower cholesterol.
These can help prevent another heart attack and heart failure. Most people who
have had a heart attack take these and sometimes other medicines for the rest
of their lives.
After you have had a heart attack, the chance that
you will have another one is higher. Taking part in a
cardiac rehab program
helps lower this risk. A cardiac
rehab program is designed for you and supervised by doctors and other
specialists. It can help you learn how to eat a balanced diet and exercise
safely to reduce your risk of more heart problems.
It is common to
feel worried and afraid after a heart attack. But if you are feeling very sad
or hopeless, ask your doctor about treatment. Getting treatment for depression
may help you recover from a heart attack.
Can you prevent a heart attack?
Heart attacks are
usually the result of heart disease, so taking steps to delay or reverse
coronary artery disease can help prevent a heart attack. Heart disease is the
number one killer of both men and women in the United States, so these steps
are important for everyone.
To improve your heart health:
- Don't smoke, and avoid secondhand smoke. Quitting smoking can
quickly reduce the risk of another heart attack or death.
- Eat a heart-healthy diet that includes plenty of fish, fruits,
vegetables, beans, high-fiber grains and breads, and olive oil.
- Get regular exercise. Your doctor can suggest a safe level of
exercise for you.
- Control your cholesterol and blood pressure.
- Manage your diabetes.
- Lower your stress level. Stress can damage your heart.
- Take a daily aspirin if your doctor advises it.
- Get a
flu
shot every year.
- Take all of your medicines correctly. Taking medicine can lower
your risk of having another heart attack or dying from coronary artery
disease.
- Seek help to manage symptoms of depression.
Frequently Asked Questions
|
Learning about heart attacks and unstable angina:
|
|
|
Being diagnosed:
|
|
|
Getting treatment:
|
|
|
Ongoing concerns:
|
|
|
Life after a heart attack:
|
|
|
End-of-life issues:
|
|
Cause
The major cause of
unstable angina
and
heart attack
is
coronary artery disease
(CAD). Coronary artery disease
occurs when
plaque
builds up over years inside your coronary
arteries and reduces blood flow to the heart muscle. In many people, coronary
artery disease begins in adolescence and gradually develops over a
lifetime.
High cholesterol, high blood pressure, and smoking
damage your arteries and contribute to plaque buildup. The process of plaque
buildup in the arteries is called
atherosclerosis
. See pictures of
atherosclerosis
and
how high blood pressure damages arteries
.
Plaques are deposits of
cholesterol
, calcium, and other substances that are
covered by a fibrous cap. If a sudden surge in blood pressure occurs, if the
artery suddenly constricts, or if other factors such as inflammation are
present, the fibrous cap can tear or rupture. The body tries to repair the
tear, much as it might stop bleeding from a cut on the skin, by forming a blood
clot over it. The blood clot can completely block blood flow through the
coronary artery to the heart muscle and cause a heart attack. See a picture of
how plaque causes a heart attack
.
But plaque is not always the cause
of a heart attack. In rare cases, the coronary artery spasms and contracts,
obstructing blood flow and causing chest pain. If severe, the spasm can
completely block blood flow and cause a heart attack. Most of the time in these
cases, atherosclerosis is also involved, although sometimes the arteries are
clear. Cocaine, cold weather, emotional stress, and other factors can cause
these spasms. But in many other cases, it is not known what triggers the
spasm.
A blood clot that forms over a ruptured plaque may not
completely block the artery but may block blood flow enough to cause unstable
angina. Unstable angina is a sign that a heart attack may soon follow, because
the blood clot can quickly grow and block the artery. If the blood clot
dissolves, and an immediate heart attack is avoided, the body will try over
time to repair the tear on the surface of the plaque. But this newly repaired
plaque can also be very unstable. It is more likely to rupture again, putting
you at even greater risk of a heart attack.
Heart attack triggers
In most cases, there are no
clear reasons why heart attacks occur when they do. But sometimes your body
releases adrenaline and other hormones into the bloodstream in response to
intense emotions such as anger, fear, and the "fight or flight" impulse. Heavy
physical exercise, emotional stress, lack of sleep, and overeating can also
trigger this response. Adrenaline increases blood pressure and heart rate and
can cause coronary arteries to constrict, which may cause an unstable plaque to
rupture.
Nicotine, which is found in tobacco products, and
cocaine can cause similar responses.
Symptoms
The most common symptom of a
heart attack
is chest pain,
although this sensation is not always present.
Women, older adults, and people with
diabetes
are slightly more likely to have other
symptoms such as shortness of breath, nausea, back pain, or jaw pain.
It is possible to have a "silent heart attack" without any symptoms, but
this is rare. Most people have chest pain and at least one other symptom, such
as:
- A feeling of choking or a "tight throat," a lump in the throat,
or a need to keep swallowing.
- A cold sweat.
- Nausea.
- A sense of impending doom.
- Difficulty breathing or breathlessness.
-
Palpitations
, or feeling your heart beat rapidly or
irregularly. (Palpitations are very common and are usually harmless in a
healthy heart, but they may signal
coronary artery disease
if brought on by
exertion.)
- Numbness or discomfort in either arm or hand.
- Weakness.
People who are having a heart attack
often describe their chest pain in various ways. The pain:
- May feel like pressure, heaviness, weight, tightness, squeezing,
discomfort, burning, a sharp ache (less common), or a dull ache. People often
put their fist to their chest when describing the pain.
- May radiate from the chest down the left shoulder and arm (the
most common site) and also to other areas, including the left shoulder, middle
of the back, upper portion of the abdomen, right arm, neck, and jaw. See a
picture of the
areas where you might have pain
during a heart attack.
- May be diffuse—the exact location of the pain is usually
difficult to point out.
- Is not made worse by taking a deep breath or pressing on the
chest.
- Usually begins at a low level, then gradually increases over
several minutes to a peak. The discomfort may come and go. Chest pain that
reaches its maximum intensity within seconds may represent another serious
problem, such as an
aortic aneurysm
.
Call
911
or your local emergency services if:
- Your chest pain gets worse or lasts more than 5 minutes,
especially if you are short of breath or feel weak, nauseated, or
lightheaded.
- Your chest pain doesn't improve or gets worse within 5 minutes
after taking 1 dose of nitroglycerin.
It may not always be possible to tell the difference
between
unstable angina
and a heart attack. Often the symptoms
are similar. Both conditions require immediate emergency care.
People who have unstable angina often describe
their pain as:
- Starting within the past 2 months and becoming more
severe.
- Limiting their physical activity.
- Suddenly becoming more frequent, severe, or longer-lasting or
being brought on by less exertion than before.
- Occurring at rest with no obvious exertion or stress. It may wake
the person up.
- Not responding to rest or nitroglycerin.
The symptoms of stable angina are different from those of
unstable angina. Stable angina occurs at predictable times with a specific
amount of exertion or activity and may continue without much change for years.
It is relieved by rest or nitrates (nitroglycerin) and usually lasts less than
5 minutes.
What Increases Your Risk
Coronary artery disease
(CAD) is the major cause of
heart attacks
. So the more risk factors you have for
CAD, the greater your risk for developing
unstable angina
or having a heart attack. Smoking,
diabetes
,
high cholesterol
,
high blood pressure
, and a
family history
of early CAD are all strong risk
factors for coronary artery disease. For more information, see the What
Increases Your Risk section of the topic
Coronary Artery Disease.
Use the
heart attack risk calculator to estimate your risk of having a heart attack
over 10 years. This tool is designed to estimate risk in adults age 20 and
older who do not have heart disease or diabetes.
Even if you
already have coronary artery disease or have had a heart attack, you can still
lower your risk of another heart attack. To lower your risk:
-
Stop smoking. Quitting smoking is probably the most important step to
decrease your chance of a heart attack. Avoid secondhand smoke too.
-
Reduce high cholesterol. High cholesterol can lead to
a buildup of cholesterol inside your arteries.
-
Lower high blood pressure. High blood pressure damages
the coronary arteries and increases the heart's workload.
-
Manage diabetes. People who have diabetes develop
hardening and narrowing of the arteries more frequently and at a younger age
than those not affected by diabetes.
-
Stay at a healthy weight. Weight loss frequently
improves blood pressure and cholesterol levels and may also help control
diabetes.
-
Be physically active. Regular exercise can help reduce
your risk of heart attack by helping you to control cholesterol and blood
pressure, regulate blood sugar (important for people with diabetes), and lose
weight. Try to do activities that raise your
heart rate
. Aim for at least 2½ hours of
moderate exercise
a week.
1
One way to do this is to be active 30 minutes a day, at least 5 days a week.
It's fine to be active in blocks of 10 minutes or more throughout your day and
week.
-
Manage depression and emotions. Treating depression
and treating anger problems are important steps in improving cardiac and
overall health and quality of life.
- Reduce stress. Stress causes increased blood pressure and heart
rate and causes your arteries to narrow, increasing your risk for heart
attack.
-
Evaluate birth control pill and hormone replacement therapy use. Birth control pills are more likely to increase a woman's risk if
she is older than 35 and smokes cigarettes. Hormone therapy (
estrogen
with or without
progestin
) may increase the risk for heart disease.
This risk is higher for some women than others.
- Take an
aspirin every day (check with your doctor first to
make sure you have no medical reasons for not taking it).
- Avoid getting sick from the
flu
. Get a flu shot every year.
- Take all of your medicines correctly. Taking medicine can lower
your risk of having another heart attack or dying from coronary artery
disease.
Some risk factors are beyond your control. These include:
Elevated levels of
C-reactive protein (CRP), a substance found in blood
that indicates
inflammation, may better predict your risk for having
a heart attack than cholesterol levels. Testing for CRP levels may help predict
heart attack risk even when a person has a normal or low level of LDL
cholesterol. And decreasing CRP levels, by taking a
statin
, may lower the risk of a heart attack in people
who have normal cholesterol levels but have high CRP levels.
2
Most
nonsteroidal anti-inflammatory drugs
(NSAIDs), which
are used to relieve pain and fever and reduce swelling and inflammation, may
increase the risk of heart attack. This risk is greater if you take NSAIDs at
higher doses or for long periods of time. People who are older than 65 or who
have existing heart, stomach, or intestinal disease are more likely to have
problems.
Aspirin, unlike other NSAIDs, has been shown to reduce
the risk of heart attack and stroke. But it also carries the risks of serious
stomach and intestinal bleeding as well as skin reactions. Regular use of other
NSAIDs, such as ibuprofen, may make aspirin less effective in preventing heart
attack and stroke.
When to Call a Doctor
Call
911
or other emergency services immediately if you have any of the following symptoms
of a heart attack:
- You have chest pain that has not improved or that gets worse
within 5 minutes after taking 1 dose of nitroglycerin and/or resting. After you
call 911, continue to stay on the phone
with the emergency operator. He or she will give you further instructions. See
how to take nitroglycerin.
- You have chest pain or discomfort that is crushing or squeezing,
feels like pressure on the chest, and gets worse or lasts more than 5 minutes,
especially if it occurs with any of the following symptoms:
- Sweating
- Shortness of breath
- Nausea or vomiting
- Pain that spreads from the chest to the neck, the jaw, or one
or both shoulders or arms
- Dizziness or lightheadedness
- A fast or irregular pulse
-
Signs of shock
Women, older adults, and people with diabetes are slightly
more likely to have other symptoms such as shortness of breath, nausea, back
pain, or jaw pain.
After you call
911 or other emergency services, you
should chew 1 adult-strengthaspirin (325 mg) or 2 to 4
low-dose aspirin (81 mg) unless you cannot take aspirin
because of allergy or some other reason. By calling
911 and taking an ambulance to the
hospital, you may be able to start treatment before you arrive at the hospital.
If any complications occur along the way, ambulance personnel are trained to
evaluate and treat them.
If an ambulance is not readily
available, have someone else drive you to the emergency room. Do not drive
yourself to the hospital.
If you witness a person become
unconscious, call 911 or other emergency
services and start CPR (cardiopulmonary resuscitation). The emergency operator
can coach you on how to perform CPR. To learn more about CPR, see the
Rescue Breathing and Cardiopulmonary Resuscitation (CPR) section of the topic
Dealing With Emergencies.
Never wait if you have symptoms of a heart attack. Many people
are unsure if they are having a
heart attack
and take a "wait and see" approach. Heart
attack symptoms can vary. People often discount their symptoms if they do not
fit into the expected "extreme chest pain" scenario. Some people are
embarrassed or don't want to bother others by calling for help if they think it
may not be a heart attack. Even if you're not sure it's a heart attack, you
should still have it checked out. Rapid treatment can save your life.
Who to See
You will be
evaluated and treated by an
emergency medicine specialist
in the emergency room.
For ongoing care, you will likely see a
cardiologist
. If surgery is needed, you will be
referred to a
cardiovascular surgeon
.
Exams and Tests
Emergency evaluation for a heart attack
After you
call 911 for a
heart attack
, paramedics will quickly assess your
heart rate, blood pressure, and breathing rate and place electrodes on your
chest for an
electrocardiogram (EKG, ECG). An electrocardiogram is
a
graphic record
of the heart's electrical activity as it contracts and relaxes.
The ECG's jagged-line image appears on a portable monitor. And in some areas
this image can be transmitted to the hospital emergency room so a doctor there
can assess your condition before you arrive.
When you arrive at
the hospital, the emergency room doctor will take your history and perform a
physical exam, and a more complete ECG will be done. An ECG can detect signs of
insufficient blood flow, heart muscle damage, abnormal heartbeats, and other
heart problems. A technician will draw blood to test for
cardiac enzymes, which are released into the
bloodstream when heart cells die. The presence of the protein troponin in the
blood usually means that there has been heart damage.
Results of
these tests are usually available quickly. If your tests show that you are at
risk of having or are having a
heart attack
, your doctor will probably recommend that
you have
cardiac catheterization. During a cardiac
catheterization, a fine tube (called a catheter) is threaded through an artery
in your arm or leg and up into the heart. Then a dye that contains iodine is
injected, which makes the coronary arteries visible on a digital X-ray screen.
The doctor can then see whether your coronary arteries are blocked and how your
heart functions.
If an artery appears blocked,
angioplasty with stent placement, a procedure to open
up clogged arteries, may be done during the catheterization, or you will be
referred to a cardiovascular surgeon for
coronary artery bypass graft surgery
.
If your tests
do not clearly indicate a heart attack or unstable
angina and you do not have other high-risk indicators (such as a previous heart
attack), you will probably have other tests, such as a myocardial perfusion
scan, also called single photon emission computed tomography or
SPECT imaging. SPECT is a noninvasive imaging scan that is often done while
you are in the emergency department to help determine whether you are at risk
of heart attack.
If your SPECT
test is abnormal, you are considered at high risk and may need cardiac
catheterization.
If your tests do not indicate a heart attack but
your doctor thinks you have unstable angina and may be in danger of having a
heart attack, you will be admitted to the hospital.
Testing after a heart attack
From 2 to 3 days
after a heart attack or after being admitted to the hospital for unstable
angina, you may have more tests to assess how well your heart is working and to
find out whether undamaged areas of the heart are still receiving adequate
blood flow.
These tests may include:
-
Echocardiogram (echo). An echo is an
ultrasound exam used to evaluate the size, thickness, shape, and movement of
the heart muscle. It also evaluates blood flow,
ejection fraction
, and the heart valves.
-
Stress electrocardiogram (such as
treadmill testing). A stress test compares your ECG while you are at rest to
your ECG after your heart has been stressed, either through physical exercise
(treadmill or bike) or by using a medicine. A stress test can detect ischemia,
which is reduced blood flow to the heart muscle.
-
Stress echocardiogram. A stress
echocardiogram can show whether you may have reduced blood flow to the
heart.
-
Cardiac perfusion scan. A thallium scan
or technetium scan (also called a sestamibi scan) is a test used to estimate
the amount of blood reaching the heart muscle during rest and exercise.
-
Angiogram. In this test, a dye
(contrast material) is injected into the coronary arteries to evaluate your
heart and coronary arteries.
-
Cardiac blood pool scan. This test shows how well your heart is pumping blood to the rest
of your body.
-
Cholesterol test. This test shows the
amounts of cholesterol in your blood.
Treatment Overview
When a
heart attack
is in progress, you need to act quickly.
Prompt treatment with medicines, angioplasty combined with stenting, or surgery
to restore blood flow soon after symptoms first begin can prevent permanent
injury to the heart muscle and save your life.
Initial treatment
If you are having a
heart attack
, the goal of your health care team will
be to prevent permanent heart muscle damage by restoring blood flow to your
heart as quickly as possible. If you are transported to the hospital in an
ambulance, you will be given
oxygen therapy
and probably
nitroglycerin or a pain reliever, such as
morphine.
Also,
aspirin (which is usually chewed on the way to the
hospital or in the emergency room),
heparin, and
antiplatelet drugs are given to prevent clots from
growing. Other medicines will be given initially to decrease your heart's
workload, improve its pumping function, and treat life-threatening abnormal
heartbeats if they occur.
The time it takes to get to a hospital
is critical because
angioplasty with or without stenting to open blocked
arteries or "clot-busting"
thrombolytic medicines to dissolve clots are most
effective if used within the first several hours after symptoms start.
Thrombolytics are given through an
intravenous
(IV) line and travel to the coronary
arteries where they break up clots.
Numerous studies have shown
that percutaneous coronary intervention (
angioplasty
with or without
stenting
) saves lives.
Although
angioplasty with or without stenting is usually the preferred treatment, it is
not available at all hospitals. So some communities are training paramedics to
identify people who have signs of heart attack so that they can be transported
directly to a heart center, even if it means bypassing a closer
hospital.
If you are treated at a hospital that has proper
equipment and staff, you may be taken to the
cardiac catheterization
lab where your doctor will
evaluate your coronary arteries to determine whether angioplasty or
coronary artery bypass graft surgery
is
appropriate.
If angioplasty with or without stenting is not
possible, either because of the location of the blockage or because of numerous
blockages, emergency coronary artery bypass surgery may be done.
If you are having unstable angina, you most likely will be admitted to the hospital and given
medicines, including aspirin, other antiplatelet medicines, and heparin. You
will be closely monitored and tested. If chest pain continues after the above
treatment and you are at high risk for heart attack, your doctor may decide to
perform coronary catheterization and plan for possible angioplasty and stent
placement to prevent a heart attack.
Ongoing treatment
After you have had a
heart attack
, you will stay in the hospital for at
least a few days so your heart rate and rhythm, blood pressure, and medicines
can be closely monitored. You will stay in the hospital because after a heart
attack you are at high risk of having serious complications, such as
life-threatening
abnormal heart rhythms
and
heart failure
.
To reduce the risk of
complications, your doctor will start you on medicines.
Angiotensin-converting enzyme (ACE) inhibitors,
angiotensin II receptor blockers (ARBs), and
beta-blockers may improve your chance of survival
after a heart attack.
Cholesterol-lowering medicines called
statins are usually given to lower your LDL
cholesterol level to less than 100 mg/dL. Cholesterol-lowering medicines can
reduce the risk of heart attack and stroke.
Aspirin, other
antiplatelet medicines such as clopidogrel (Plavix),
or anticoagulants (such as warfarin) may be used after a
heart attack. These medicines are used to lower the risk of another heart
attack and to prevent blood clots from forming in the heart, which could break
loose and travel to the brain, causing a
stroke
. If you take warfarin (Coumadin), see:
-
Anticoagulants: Vitamin K and your diet.
The amount of heart muscle that is permanently damaged
may be less than it appears immediately after a heart attack has occurred. Some
heart tissue may be "stunned myocardium," or heart muscle that is not able to
contract normally at first but is later able to function normally. Your heart's
pumping capacity will be closely monitored and your treatment adjusted as
needed during this time.
Research highlights the importance of
quitting smoking after a heart attack. People who continue to smoke after a
heart attack are much more likely than nonsmokers to have another heart attack.
Among those who stop smoking, their risk starts decreasing a lot in the first
year they stop smoking. Their risk keeps dropping until it becomes the same as
the risk for nonsmokers in about 3 years.
If you smoke, your doctor will strongly advise that you
quit and avoid secondhand smoke too. Your doctor may prescribe medicine and
therapy to help you do so. Studies show that
nicotine replacement therapy, use of the medicine
bupropion (such as Zyban or Wellbutrin), and
supportive therapy significantly increase long-term success in
quitting.
3,
4
For more
information on how to quit, see the topic
Quitting Smoking.
After a heart attack,
you are a candidate for
cardiac rehabilitation to lower your risk of death
related to heart disease. Rehabilitation (rehab) and lifestyle changes are an
important part of your recovery after a heart attack. For more information, see
the topic
Cardiac Rehabilitation.
If you do not
participate in a cardiac rehab program, you will still need to learn about
necessary lifestyle changes, such as quitting smoking, eating a low-fat diet,
and perhaps starting an exercise program.
Avoid getting sick from
the
flu
. Get a flu shot every year.
Treatment if the condition gets worse
Heart attacks
that damage crucial or large areas of the heart tend to cause more
complications later. If only a small amount of heart muscle dies, the heart may
still function normally after a heart attack.
Scar tissue
eventually replaces the areas of heart muscle tissue that are damaged by a
heart attack. Scar tissue limits your heart's ability to pump effectively.
Damage to the
left ventricle
can limit the heart's capacity to pump.
This damage can lead to
heart failure
.
If the heart attack
damaged the area of your heart that regulates your heart rate, your heart can
develop abnormal heart rhythms, called
arrhythmias
. In this case, you may need a
pacemaker
, which is a device that stimulates the heart
to beat and regulates the heart rate, and possibly medicines to control your
heart rhythms. Some arrhythmias also increase your risk for
stroke
.
The chance that these
complications will develop depends on the amount of heart tissue affected by a
heart attack and whether medicines are given during and after a heart attack to
help prevent these complications. Other factors, such as your age and general
health, also determine your risk of complications and death.
Palliative care
If your condition gets worse, you
may want to think about
palliative care
. Palliative care is a kind of care for
people who have illnesses that do not go away and often get worse over time. It
is different than care to cure your illness, called curative treatment.
Palliative care focuses on improving your quality of life—not just in your
body, but also in your mind and spirit. Some people combine palliative care
with curative care.
Palliative care may help you manage symptoms
or side effects from treatment. It could also help you cope with your feelings
about living with a long-term illness, make future plans for your medical care,
or help your family better understand your illness and how to support
you.
If you are interested in palliative care, talk to your
doctor. He or she may be able to manage your care or refer you to a doctor who
specializes in this type of care.
For more information, see the
topic
Palliative Care.
Prevention
The percentage of Americans who have a
heart attack
, as well as the number of resulting
deaths, has continued to decrease since the 1970s. This decrease is due to both
advances in medicine and lifestyle changes that people are making to prevent
coronary artery disease (CAD)
and heart attack.
Important lifestyle changes that you can make are to quit smoking and to
get plenty of exercise. Eating a
balanced diet that is low in saturated fats and rich
in fruits and vegetables is also advised.
Lifestyle changes may include:
General dietary guidelines for
heart-healthy eating may be recommended, such as the:
Specific dietary considerations
involve:
Cholesterol
Having high cholesterol increases
your risk of coronary artery disease. If diet and exercise are not effective in
lowering your cholesterol to a safe level, your doctor will probably prescribe
a statin, a cholesterol-lowering medicine. These
medicines have been proved effective in treating high cholesterol. And now
doctors are beginning to prescribe them for people with lower cholesterol
levels. Cholesterol-lowering drugs can also help people with normal to
moderately high levels of cholesterol. In these people, cholesterol-lowering
drugs combined with lifestyle changes may slow the development of
atherosclerosis
and lower the risk of heart attack or
death.
Aspirin
Aspirin may reduce the risk of
developing blood clots that can lead to a heart attack in people with known CAD
and in people with multiple risk factors for CAD, such as
diabetes
,
high blood pressure
, and
high cholesterol
. There are some risks associated with
aspirin therapy that you should discuss with your doctor before you begin this
type of treatment. If you cannot take aspirin, your doctor may prescribe
another
antiplatelet medicine, such as clopidogrel (Plavix).
For more information, see:
-
Should I take daily aspirin to prevent a heart attack or a stroke?
Hormone therapy
Taking
estrogen
with or without
progestin
does not prevent coronary artery disease. In
fact, if you are 10 or more years past
menopause
, taking
hormone therapy
may raise your risk of coronary artery
disease.
5
Talk to your doctor about your
risks with hormone therapy. And carefully weigh the
benefits against the risks of taking it. If you need
relief for symptoms of menopause, hormone therapy is one choice you can think
about. But there are other types of treatment for problems like hot flashes and
sleep problems. For more information, see the topic
Menopause and Perimenopause.
Ongoing Concerns
After you've had a
heart attack
, your biggest concern will probably be
that you could have another one. Taking your medicines as directed will be an
important part of preventing another heart attack. Medicines commonly
prescribed after a heart attack include drugs to:
- Prevent blood clots.
- Decrease the work of your heart.
- Improve your heart’s pumping ability.
- Lower cholesterol.
- Treat irregular heartbeats.
- Lower blood pressure.
Understanding what
coronary artery disease
(CAD) is and how to treat it
may help prevent a future heart attack. For more information, see the topic
Coronary Artery Disease.
Your doctor will
want to closely monitor you after a heart attack. Be sure to keep all your
appointments. Tell your doctor about any changes in your condition, such as
changes in chest pain, weight gain or loss, shortness of breath with or without
exercise, and feelings of depression.
About half of all people who
have a heart attack will experience a serious complication. The kinds of
complications you may have depend upon the location and extent of the heart
muscle damage. The most common complications are:
- Abnormal heart rhythms, called
arrhythmias
. These include life-threatening
ventricular tachycardia, which is a rapid heart rate, and
atrial fibrillation
, a type of irregular
heartbeat.
-
Heart failure
, which can be short-term or can become a
lifelong condition.
Managing angina
You should notify your doctor
about any chest pain or discomfort (
angina
) you
have after a heart attack, because it will probably be treated more
aggressively and may indicate that you are at risk for another heart attack.
Many people have stable angina, which is predictable and diminishes after
taking
nitroglycerin (a medicine to control angina) and
resting.
Nitroglycerin is often prescribed to be taken on an
as-needed basis for angina. In most cases, you may take 1 nitroglycerin tablet
or 1 dose if you use the spray form. If after 5 minutes the chest pain doesn't
improve or gets worse, call 911
or other emergency services immediately. Stay on the phone with the emergency
operator—he or she will give you further instructions.
See
how to use nitroglycerin for sudden chest pain. Keep nitroglycerin with you
at all times. Some doctors recommend that you use it before you exercise or
exert yourself, to prevent an angina attack.
Life After a Heart Attack
Coming home after a heart
attack may be unsettling. Your hospital stay may have seemed too short. You may
be nervous about being home without medical oversight after being so closely
attended to in the hospital. But you have had tests that tell your doctor that
it is safe for you to return home. Also, to reduce your risk of having another
heart attack
, your doctor may recommend that
you:
- Quit smoking and avoid secondhand smoke. Quitting smoking may be
the most important step you can take to reduce your risk. Evidence suggests
that the risk of death or recurrent heart attack is rapidly reduced for people
with
coronary artery disease
who stop smoking. For more
information, see the topic
Quitting Smoking.
-
Be physically active. Talk with your doctor about
exercising safely and about enrolling in a cardiac rehabilitation program.
Regular exercise can help reduce your risk of another heart attack by helping
you control cholesterol and blood pressure, regulate blood sugar (important for
people with diabetes), and lose weight. See the Cardiac Rehabilitation topic.
Before you start an exercise program or do any strenuous exercise, your doctor
can do pre-exercise testing to find out your risk for heart attack. For more
information, see the following:
-
Heart disease: Exercising for a healthy heart
- Take an
aspirin every day. If you have a stent, you may also
take an
antiplatelet medicine, such as clopidogrel (Plavix).
- Lower your cholesterol by taking medicines such as statins or
other lipid-lowering medicines. Lowering cholesterol can reduce the risk for
another heart attack.
- Control your blood pressure by taking medicines as directed by
your doctor. Some nutrients in the diet can affect blood pressure. See
nutrition for hypertension (including the DASH diet)
for more information about this eating plan, which has been proved to lower
blood pressure. Also see:
-
High blood pressure: Using the DASH diet.
- Keep your blood sugar under control if you have diabetes. Having
high blood sugar over a long period of time is linked with developing heart
disease. The American Diabetes Association and the American Heart Association
recommend that people with diabetes have an
hemoglobin A1c level of less than 7%.
6
- Follow a
heart-healthy diet. A heart-healthy diet includes
eating more fish. You may also follow the
Mediterranean diet. A heart-healthy diet may help you
lose weight, lower your blood pressure, and reduce your cholesterol. For more
information, see:
-
Heart disease: Eating a heart-healthy diet.
-
Reduce stress. Stress management may lower rates of
heart attack or death in people with coronary artery disease.
- Participate in a
cardiac rehabilitation program. You will learn how to
exercise safely, change habits that put you at risk for another heart attack,
and deal with stress and emotional issues. Studies have found that cardiac
rehab reduces your risk of having another heart attack.
- Avoid getting sick from the
flu
. Get a flu shot every year.
- If you drink alcohol, drink moderately (1
alcoholic drink
a day for women or 2 drinks a day for men). Drinking alcohol
moderately, along with living a healthy lifestyle, may lower your risk for a
heart attack or
complications after a heart attack. Although studies
show that wine may be beneficial, the link between wine and reduced coronary
artery disease has not been proved. Ask your doctor about the benefits and
risks of drinking alcoholic beverages.
- Seek help for depression. Having a heart attack is scary, and
depression afterward is common. Asking for and receiving support from friends
and relatives can help you avoid depression. If you continue to feel depressed,
talk to your doctor about counseling and medicine for depression. People who
get treatment for depression may recover better after a heart attack than those
who do not. For more information, see the topic
Depression.
-
Resume sexual activity after a heart attack. One
common myth is that resuming sex after a heart attack can cause another heart
attack, stroke, or sudden death. According to the American Heart Association,
people who have had heart attacks can resume sexual activity as soon as they
feel ready for it. Talk with your doctor if you have any concerns. If you take
a nitrate, like nitroglycerin, do not take
erection-enhancing medicines. Combining these
medicines can cause a life-threatening drop in blood pressure.
- Seek
help for sleep problems. Your doctor may want to check for
sleep apnea
, a common sleep problem in people with
heart disease. For more information, see
Sleep Apnea.
Most often the cause of a heart attack is
coronary artery disease
(CAD). Knowing what CAD is and
how to treat it may help prevent a future heart attack. For more information,
see the topic
Coronary Artery Disease.
Medications
Medicines for unstable angina
Certain medicines can help keep blood from clotting, reduce
the risk that unstable angina may develop into a
heart attack
, and decrease your chance of dying. These
include:
-
Aspirin.
-
Antiplatelet medicines, such as clopidogrel (Plavix).
-
Anticoagulants, such as heparin, enoxaparin (Lovenox),
dalteparin (Fragmin), and bivalirudin (Angiomax). Some anticoagulants, such as
bivalirudin, are only used in the hospital.
Medicines that decrease the heart's workload, improve
blood flow to the heart, and relieve chest pain are usually given to people
with
unstable angina
who are at risk of heart attack. These
medicines include:
-
Morphine.
-
Nitrates, such as nitroglycerin or isosorbide
dinitrate (for example, Isordil).
-
Beta-blockers, such as carvedilol (Coreg) or
metoprolol (for example, Lopressor).
In some cases, other medicines may be used, including:
Medicines for a heart attack in progress
Medicines
for a heart attack work to open the blocked artery to restore blood flow as
fast as possible and to decrease the workload on the heart.
Medicines after a heart attack
After a heart
attack, your doctor may give you medicines to prevent
heart failure
and prevent or reduce the risk of
irregular heartbeats (
arrhythmias
), both of which can happen
after a heart attack. These medicines include:
Your doctor may also give you medicines to prevent blood
clots from forming and causing a stroke or another heart attack. These
medicines include:
If you have high cholesterol, your doctor may prescribe
cholesterol-lowering medicines called
statins to prevent future heart attacks.
Nitrates may be used to control remaining angina
symptoms.
Aldosterone receptor antagonists may be used to help your
body get rid of extra salt and water. They are a type of
diuretic
.
What to Think About
Take all of your medicines
correctly. Taking medicine can lower your risk of having another heart attack
or dying from coronary artery disease.
Do not substitute
nonsteroidal anti-inflammatory drugs (NSAIDs)
, such as
ibuprofen (Advil, for example) or naproxen (such as Aleve), for aspirin.
Although NSAIDS relieve pain and inflammation much like aspirin does, they may
increase your risk for a heart attack or stroke.
If you had
angioplasty
and got a
stent
, you will take antiplatelet medicines to help
prevent another heart attack or a stroke. You will probably take aspirin plus
another antiplatelet such as clopidogrel (Plavix). If you get a drug-eluting
stent, you will probably take both of these medicines for at least one year. If
you get a bare metal stent, you will take both medicines for at least one month
but maybe up to one year. Then you will likely take daily aspirin long-term. If
you have a high risk of bleeding, your doctor may shorten the time you take
these medicines.
Surgery
Coronary artery bypass graft surgery (CABG) may be
done on an emergency basis to treat a
heart attack
.
Coronary artery bypass
grafting, also called bypass surgery or "cabbage," may be needed when a heart
attack cannot be safely and effectively treated with medicine or angioplasty.
For example, bypass surgery may be done when there are blockages in the
coronary arteries that cannot be reached during
angioplasty or if angioplasty was tried but did not
sufficiently widen the blood vessel. Also, bypass surgery is often recommended
for people with
diabetes
.
What to Think About
If muscles holding the heart
valve in proper position were damaged by the heart attack, heart valve repair
or replacement may be done at the same time as a coronary artery bypass.
After a heart attack, or after you have had angioplasty or bypass
surgery, you may be encouraged to participate in a
cardiac rehabilitation program to help lower your risk
of death related to heart disease. For more information, see the topic
Cardiac Rehabilitation.
Other Treatment
If your heart rate is too slow
(
bradycardia
), your doctor may recommend a
pacemaker.
If you have abnormal heart
rhythms or if you are at risk for abnormal heart rhythms that are
life-threatening, your doctor may recommend an
implantable cardioverter-defibrillator (ICD).
For information about living with a pacemaker or ICD, see:
-
Heart problems: Living with a pacemaker or ICD.
What to Think About
Try to follow a healthy
lifestyle with regular exercise and a healthy diet instead of relying on
vitamin supplements for nutrition and heart health. Talk with your doctor
before taking any nutrition supplements. For example, you should probably not
take folate therapy (a combination of folic acid, vitamin B6, and vitamin
B12).
End-of-Life Decisions
Treatment for a
heart attack
is increasingly successful at prolonging
life and reducing complications and hospitalization. But a heart attack can
lead to progressive, fatal conditions, such as
heart failure
and abnormal heart rhythms (
arrhythmias
).
Many important end-of-life decisions can be made while you are active and able
to communicate your wishes.
When you are diagnosed with a heart
attack, your doctor will discuss treatment options with you. Your doctor may
talk to you about your desire to be revived (resuscitated) if your heart stops
pumping and you are unable to breathe on your own. You may want to learn more
about aggressive life-sustaining medical treatment and whether it is right for
you. For more information, see:
-
Should I receive CPR and mechanical ventilation?
Many other decisions about end-of-life issues, such as
writing a living will and estate planning, can be made in advance, leaving
valuable time that can be spent with loved ones and on other important matters.
For more information, see the topics
Care at the End of Life and
Writing an Advance Directive.
Other Places To Get Help
Organizations
|
American Heart Association (AHA)
|
| 7272 Greenville Avenue |
| Dallas, TX 75231 |
| Phone: |
1-800-AHA-USA1 (1-800-242-8721) |
| Web Address: |
www.americanheart.org |
| |
|
Call the American Heart Association (AHA) to find your
nearest local or state AHA group. AHA can provide brochures and information
about support groups and community programs, including Mended Hearts, a
nationwide organization whose members visit people with heart problems and
provide information and support. AHA's Web site also has information on
physical activity, diet, and various heart-related conditions.
|
|
|
HeartHub
|
| Web Address: |
www.hearthub.org |
| |
|
HeartHub is a patient Web site from the American Heart
Association. It provides patient-focused information, tools, and resources
about heart diseases and stroke. The site helps you understand and manage your
health. It includes online tools that explain your risks and treatment options.
The site includes articles, the latest news in health and research, videos,
interactive tools, forums and community groups, and e-newsletters.
The Web site includes health centers that cover heart rhythm problems,
cardiac rehabilitation, caregivers, cholesterol, diabetes, heart attack, heart
failure, high blood pressure, peripheral artery disease, and stroke.
HeartHub also links to Heart360.org, another American Heart Association
Web site. Heart360 is a tool that helps you send and receive medical
information with your doctor. It also helps you monitor your health at home. It
gives you access to tools to manage and monitor high blood pressure, diabetes,
high cholesterol, physical activity, and nutrition.
|
|
|
National Heart, Lung, and Blood Institute
(NHLBI)
|
| P.O. Box 30105 |
| Bethesda, MD 20824-0105 |
| Phone: |
(301) 592-8573 |
| Fax: |
(240) 629-3246 |
| TDD: |
(240) 629-3255 |
| E-mail: |
nhlbiinfo@nhlbi.nih.gov |
| Web Address: |
www.nhlbi.nih.gov |
| |
|
The U.S. National Heart, Lung, and Blood Institute
(NHLBI) information center offers information and publications about preventing
and treating:
- Diseases affecting the heart and circulation, such as heart
attacks, high cholesterol, high blood pressure, peripheral artery disease, and
heart problems present at birth (congenital heart diseases).
- Diseases that affect the lungs, such as asthma, chronic
obstructive pulmonary disease (COPD), emphysema, sleep apnea, and
pneumonia.
- Diseases that affect the blood, such as anemia,
hemochromatosis, hemophilia, thalassemia, and Von Willebrand disease.
|
|
|
National Institutes of Health Senior
Health
|
| 9000 Rockville Pike |
| Bethesda, MD 20892 |
| Phone: |
(301) 496-4000 |
| E-mail: |
custserv@nlm.nih.gov |
| Web Address: |
www.NIHSeniorHealth.gov |
| |
|
This Web site for older adults offers aging-related
health information. The Web site's senior-friendly features include large
print, simple navigation, and short, easy-to-read segments of information. A
visitor to this Web site can click special buttons to hear the text aloud, make
the text larger, or turn on higher contrast for easier viewing.
The
site was developed by the National Institute on Aging (NIA) and the National
Library of Medicine (NLM), both part of the National Institutes of Health
(NIH). NIHSeniorHealth features up-to-date health information from NIH. Also,
the American Geriatrics Society provides independent review of some of the
material found on this Web site.
|
|
|
Women's Heart Foundation
|
| Phone: |
(609) 771-9600 |
| Fax: |
(609) 771-3778 |
| E-mail: |
bonnie@womensheart.org |
| Web Address: |
www.womensheart.org |
| |
|
The Women's Heart Foundation provides education for
women about preventing and treating heart disease. Information covers
caregiving, exercise, nutrition, and medical and surgical treatments. The
information focuses on the unique needs of women who have heart disease.
|
|
References
Citations
-
U.S. Department of Health and Human Services (2008).
2008 Physical Activity Guidelines for Americans (ODPHP
Publication No. U0036). Washington, DC: U.S. Government Printing Office.
Available online:
http://www.health.gov/paguidelines/pdf/paguide.pdf.
-
Ridker PM, et al. (2008). Rosuvastatin to prevent
vascular events in men and women with elevated C-reactive protein.
New England Journal of Medicine, 359(21):
2195–2207.
-
Stead LF, et al. (2008). Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews (1).
-
Hughes JR, et al. (2007). Antidepressants for smoking
cessation. Cochrane Database of Systematic Reviews
(2).
-
Rossouw JE, et al. (2007). Postmenopausal hormone
therapy and risk of cardiovascular disease by age and years since menopause.
JAMA, 297(13): 1465–1477.
-
American Diabetes Association (2009). Standards of
medical care in diabetes. Clinical Practice Recommendations 2009.
Diabetes Care, 32(Suppl 1): S13–S61.
Other Works Consulted
-
American Heart Association and American College of
Cardiology (2006). AHA/ACC guidelines for secondary prevention for patients
with coronary and other atherosclerotic vascular disease: 2006 update.
Circulation, 113(19): 2363–2372. [Erratum in
Circulation, 113(22): 847.]
-
Antman EM, et al. (2004). ACC/AHA guidelines for
management of patients with ST-elevation myocardial infarction. Executive
summary: A report of the American College of Cardiology/American Heart
Association Task Force on Practice Guidelines (Writing Committee to Revise the
1999 Guidelines for the Management of Patients with Acute Myocardial
Infarction). Circulation, 110(5): 588–636.
-
Bhatt DL, et al. (2008). ACCF/ACG/AHA 2008 Expert
consensus document on reducing the gastrointestinal risks of antiplatelet
therapy and NSAID use. A report of the American College of Cardiology
Foundation Task Force on Clinical Expert Consensus Documents. Circulation, 118(18): 1894–1909.
-
De Lemos JA, O'Rourke RA (2008). Unstable angina and
non-ST-segment elevation myocardial infarction. In V Fuster et al., eds.,
Hurst's The Heart, 12th ed., pp. 1351–1374. New York:
McGraw-Hill Medical.
-
Epstein AE, et al. (2008). ACC/AHA/HRS 2008 Guidelines
for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the
American College of Cardiology/American Heart Association Task Force on
Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002
Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia
Devices): Developed in Collaboration With the American Association for Thoracic
Surgery and Society of Thoracic Surgeons. Circulation,
117(21): e350–e408.
-
Hirsch J, et al. (2008). Executive summary: American
College of Chest Physicians evidence-based clinical practice guidelines (8th
ed.). Chest, 133(6): 71–109.
-
King SB III, et al. (2007). 2007 focused update of the
ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: A
report of the American College of Cardiology/American Heart Association Task
Force on Practice Guidelines. Circulation, 117(2):
261–295. Originally published online December 13, 2007
(doi:10.1161/circulationaha.107.188208).
-
Kloner RA, Birnbaum Y, eds. (2006). Cardiovascular Trials Review, 10th ed. CD ROM, Interactive
2006, version 3.0. Hoboken, NJ: Le Jacq.
-
Krumholz HM, et al. (2008). ACC/AHA 2008 Performance
measures for adults with ST-elevation and Non ST-elevation myocardial
infarction. A report of the American College of Cardiology/American Heart
Association Task Force on Performance Measures (Writing Committee to Develop
Performance Measures for ST-Elevation and Non ST-Elevation Myocardial
Infarction). Circulation, 118(24):
2596–2648.
-
Lichtman JH, et al. (2008). Depression and coronary
heart disease: Recommendations for screening, referral, and treatment: A
science advisory from the American Heart Association Prevention Committee of
the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council
on Epidemiology and Prevention, and Interdisciplinary Council on Quality of
Care and Outcomes Research: Endorsed by the American Psychiatric Association.
Circulation, 118(17): 1768–1775.
-
Lloyd-Jones D, et al. (2009). Heart disease and stroke
statistics 2009 update. Circulation, 119(3): e21–e181.
Available online:
http://circ.ahajournals.org/cgi/reprint/CIRCULATIONAHA.108.191261.
-
Malenka DJ, et al. (2008). Outcomes following coronary
stenting in the era of bare-metal vs the era of drug-eluting stents.
JAMA, 299(24): 2868–2876.
-
Sabik JF (2007). Coronary artery bypass surgery. In EJ
Topol, ed., Textbook of Cardiovascular Medicine, 3rd
ed., pp. 1290–1305. Philadelphia: Lippincott Williams and Wilkins.
-
Somers VK, et al. (2008). Sleep apnea and
cardiovascular disease: An American Heart Association/American College of
Cardiology Foundation Scientific Statement from the American Heart Association
Council for High Blood Pressure Research Professional Education Committee,
Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular
Nursing in collaboration with the National Heart, Lung, and Blood Institute
National Center on Sleep Disorders Research (National Institutes of Health).
Circulation, 118(10): 1080–1111.
-
U.S. Preventive Services Task Force (2009).
Aspirin for the Prevention of Cardiovascular Disease.
Rockville, MD: Agency for Healthcare Research and Quality. Available online:
http://www.ahrq.gov/clinic/uspstf/uspsasmi.htm.
-
Wilkoff BL, et al. (2008). HRS/EHRA expert consensus
on the monitoring of cardiovascular implantable electronic devices (CIEDS):
Description of techniques, indications, personnel, frequency and ethical
considerations. Heart Rhythm, 5(6): 907–925. Available
online:
http://www.hrsonline.org/Policy/ClinicalGuidelines/upload/cieds_guidelines.pdf.
-
Wright RS (2008). Unstable angina and other acute
coronary syndromes. In DC Dale, DD Federman, eds., ACP Medicine, section 1, chapter 10. Hamilton, ON: BC Decker.
-
Yang EH, et al. (2008). ST-segment elevation
myocardial infarction. In V Fuster et al., eds., Hurst's The Heart, 12th ed., pp. 1375–1404. New York: McGraw-Hill Medical.
Credits
|
Author
|
Robin Parks, MS |
|
Editor
|
Kathleen M. Ariss, MS |
|
Associate Editor
|
Pat Truman, MATC |
|
Primary Medical Reviewer
|
Caroline S. Rhoads, MD - Internal Medicine |
|
Specialist Medical Reviewer
|
John A. McPherson, MD, FACC, FSCAI - Cardiology |
|
Last Updated
|
May 5, 2009 |
U.S. Department of Health and Human Services (2008).
2008 Physical Activity Guidelines for Americans (ODPHP
Publication No. U0036). Washington, DC: U.S. Government Printing Office.
Available online:
http://www.health.gov/paguidelines/pdf/paguide.pdf.
Ridker PM, et al. (2008). Rosuvastatin to prevent
vascular events in men and women with elevated C-reactive protein.
New England Journal of Medicine, 359(21):
2195–2207.
Stead LF, et al. (2008). Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews (1).
Hughes JR, et al. (2007). Antidepressants for smoking
cessation. Cochrane Database of Systematic Reviews
(2).
Rossouw JE, et al. (2007). Postmenopausal hormone
therapy and risk of cardiovascular disease by age and years since menopause.
JAMA, 297(13): 1465–1477.
American Diabetes Association (2009). Standards of
medical care in diabetes. Clinical Practice Recommendations 2009.
Diabetes Care, 32(Suppl 1): S13–S61.
|